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Semax
Semax (ACTH 4-10 Analog)
Low Risk
Cognitive
A synthetic ACTH(4-10) analog registered as a nootropic in Russia. Upregulates BDNF and modulates dopamine/serotonin for enhanced focus, learning, and memory.
Benefits
Boosts focus, learning, and memory
Upregulates BDNF (brain-derived neurotrophic factor)
Modulates dopamine and serotonin pathways
Neuroprotective (stroke recovery, TBI)
May help with ADHD symptoms
Supports nerve regeneration
Side Effects & Risks
Generally well toleratedmild
Nasal dryness/irritationmild
Rare headachemild
Potential overstimulation at high dosesmoderate
Dosing Information
Typical Dose
200-600 mcg/day (0.1% solution)
Administration
Intranasal spray
Cycle Length
5-14 day cycles
Notes
0.1% for nootropic use. 1% reserved for neurological conditions.
Legal Status
FDA Status
Not FDA-approved in USA
Availability
Registered nootropic in Russia; research chemical in US
WADA Status
Not currently banned
Evidence
Evidence LevelModerate
Decades of Russian clinical use. Published studies on BDNF upregulation. Limited Western clinical trial data.
Works Well In These Stacks
Where to Buy
Available from verified suppliers
BiosynTech Research Verified4.5
View Supplier Semax Research Vial
LyophilizedPurity: 98%+
COA Available Third-Party TestedIn Stock
NeuroPep Sciences4.6
View Supplier Semax Nasal Spray (0.1%)
Nasal SprayPurity: 99%+
COA Available Third-Party TestedIn Stock
NeuroPep Sciences4.6
View Supplier Semax Nasal Spray (1% N-Acetyl)
Nasal SprayPurity: 99%+
COA Available Third-Party TestedOut of Stock