Ipamorelin

Ipamorelin Acetate

Low Risk

Muscle GrowthFat LossAnti-AgingSleep & Wellness

A selective GH secretagogue that mimics ghrelin without triggering appetite or affecting cortisol/prolactin. Considered one of the safest GH peptides.

Benefits

Selective GH release without cortisol/prolactin spikes

Promotes lean muscle growth

Accelerates fat loss while preserving muscle

Improves deep sleep quality

Enhances recovery and wound healing

Does not significantly increase appetite

Side Effects & Risks

Mild headache (first 1-2 weeks)mild

Initial fatiguemild

Injection site irritationmild

Mild water retentionmild

Dosing Information

Typical Dose

200-300 mcg, 1-3 times daily

Administration

Subcutaneous injection

Cycle Length

8-12 weeks on, 4 weeks off

Notes

Typically at night. Best combined with CJC-1295 for 3-5x GH increase.

Legal Status

FDA Status

Not FDA-approved

Availability

Removed from Category 2 Sept 2024; some compounding pharmacies

WADA Status

Banned by WADA (athletes beware)

Evidence

Evidence LevelLow-Moderate

Limited to a single 1998 characterization study. Well-tolerated anecdotally but lacks modern RCTs. Most evidence is extrapolated from the GHS receptor mechanism.